Please Join Us

Please join us at the Tumor, Transplant and Tolerance (TTT) Retreat. The goal of the retreat is to foster cross-talk between investigators with a research focus on immune tolerance in different disease systems. In addition to a fantastic keynote talk and an impressive faculty line up of speakers, there will also be opportunities for trainees to present their research projects. The retreat will feature the following sessions: I. Autoimmunity: Tolerance Breakdown and How to Fix It; 2. Tumors: Too Much Tolerance and How to Break It; 3. We Need Tolerance and How to Enforce It. REGISTRATION DEADLINE: APRIL 28.

Distinguished speakers, Friday, May 5, 2017 - MORNING
Mark Shlomchik, MD, PhD, UPMC Endowed Professor of Immunology and Chair, Dept. of Immunology
How Autoimmunity Gets Started
Distinguished speakers
Mandy McGeachy, PhD, Assistant Professor, Div. of Rheumatology & Clinical Immunology, Dept. of Medicine
Too Much of a Good Thing: Th17 Regulation in Autoimmunity
Distinguished speakers
Olja Finn, PhD, Distinguished Professor, Depts. of Immunology and Surgery
Human Tumor Antigens Then and Now
Distinguished speakers
Greg Delgoffe, PhD, Assistant Professor, Dept. of Immunology
Tumor Microenvironment Metabolism: A New Checkpoint to Effective Antitumor Immunity
Distinguished speakers
Jeremy Tilstra, MD, PhD, Fellow, Dept. of Rheumatology and Clinical Immunology/Laboratory of Dr. Mark Shlomchik
T Cell Exhaustion in Lupus Nephritis: A Key to Understanding Autoimmunity and the Adverse Effects of Checkpoint Blockade
Distinguished speakers
Abigail E. Overacre-Delgoffe, Graduate Student, Dept. of Immunology/Laboratory of Dr. Dario Vignali
Interferon-y Drives Treg Fragility to Promote Anti-Tumor Immunity
Distinguished Speakers, Friday, May 5, 2017 - AFTERNOON
David Rothstein, MD, Pittsburgh Steelers Chair in Transplantation; Professor, Depts. of Surgery , Medicine and Immunology
A Tale of Two TIMs: Modulation of the Immune Response by Regulatory and Inflammatory B Cells
Distinguished Speakers
Warren Shlomchik, MD, Visiting Professor, Depts. of Medicine, Hematology-Oncology and Immunology
Mechanisms of Graft-vs-Host Disease and Graft-vs-Leukemia
Distinguished Speakers
Faruk Sacirbegovic, PhD, Postdoctoral Associate, Dept. of Medicine/Laboratory of Dr. Warren D. Shlomchik
Identifying the Clonal Origins of GVHD-inducing T Cells
Distinguished Speakers
KEYNOTE SPEAKER - Marcel van den Brink, MD, PhD, Head, Div. of Hematologic Oncology; Alan N. Houghton Chair; Memorial Sloan Kettering Cancer Center
Strategies to Enhance Hematopoietic Stem Cell Transplantation

Poster Sessions

ABSTRACT SUBMISSION GUIDELINES:

Timeline: All abstracts that wish to be considered for oral presentation are due by midnight on April 10, 2017.  This will allow for scoring of the abstracts and selection of the trainee talks by April 24, 2017. If you do not wish to be considered for oral presentation, abstracts for posters ONLY will be accepted until April 17, 2017 at midnight. One trainee per section (transplant, tumor and tolerance) will be selected for an oral presentation.

Eligibility: Graduate students, postdocs, clinical fellows (or equivalent)

Format: All abstracts should not exceed 300 words in length. This does not include the title, authors, or funding source (optional).  There should be no figures within the abstract. The trainee should select the TTT section that is most applicable to their abstract for scoring purposes (transplant, tumor and tolerance). The sections of the abstract should be Introduction, materials and methods, results, and conclusions (per the template provided).

Scoring: All abstracts will be scored on an NIH scale and three components: scientific content, innovation/significance and clarity of the concept. Each component will receive a score from 1 to 9 (1= highest and 9=lowest) and the scores will be combined for a total score.  Each abstract will be reviewed by two experts within the fields of transplant, tumors and tolerance. The scores of the judges will be averaged and the trainee with the lowest average score will receive the oral presentation slot for the 2017 TTT meeting. On the day of the retreat, posters will be scored in the same manner, with an additional section to score poster presentation.

Awards: The top abstract for each section will receive an oral presentation.  These trainees will also participate in the poster presentations to receive feedback on their work, however, they will not be part of the poster competition.  Each section (transplant, tumor and tolerance) will have three prizes for posters based on the judges’ scores.  Each poster will receive two judges. The trainees that receive the top score for poster presentation will be awarded a talk at next year’s TTT retreat.

Poster sessions will be held the day of the Retreat, Friday, May 5.  Participants must complete the attached form and provide it to Carla Forsythe (forsythecj@upmc.edu) by midnight, April 10, to be considered for oral presentation.  Posters will be assigned numbers, with the odd numbers presenting in the morning and the even numbers presenting in the afternoon session.  Presenters are asked to please leave their posters up throughout both sessions.  They may be taken down at the conclusion of the retreat.

Dimensions of posters should not exceed 4'x4'.  Poster boards with pins and numbers will be provided.

The organizing committee hopes that you'll encourage your postdocs and students to participate ... and we look forward to a great day of science and socializing!